Arthur Vithran Orthopaedic surgeon and researcher

Research

Research and publications

Selected work across osteoarthritis, joint biology, sports medicine, reconstruction, foot and ankle care, osteoporosis, rehabilitation, and musculoskeletal ageing.

The programme connects orthopaedic care with the biology of bone, joint, and muscle across ageing. Hypotheses, evidence syntheses, clinical studies, and treatment recommendations are kept distinct.

Evidence boundary: laboratory promise is not presented as proven clinical benefit.

Bibliographic record checked
11 August 2026

Selected titles, journals, years, DOIs, and authorship were checked against DOI registry metadata. Dynamic profile counters and review-count figures are intentionally not displayed.

Selected work

Research themes

These entries are a selection, not a complete bibliography. Each title links to its DOI record. Use the authoritative profiles below for live records.

Programme 01

Osteoarthritis: inflammation & joint biology

Reviews of immune signalling, extracellular-matrix turnover, and lymphatic biology in musculoskeletal disease. Candidate mechanisms are not presented as proven patient benefit.

  1. The role of the lymphatic system in musculoskeletal system health and disease: research progress and future directions

    Narrative review of current evidence and research directions across musculoskeletal health and disease.

    Bone Research · 2026 · DOI verified
  2. CC chemokines and receptors in osteoarthritis: new insights and potential targets

    Review of proposed chemokine roles and candidate targets in osteoarthritis; not a clinical treatment recommendation.

    Arthritis Research & Therapy · 2023 · DOI verified
  3. HYBID in osteoarthritis: potential target for disease progression

    Review of evidence concerning the hyaluronan-degrading enzyme HYBID and its status as a candidate research target.

    Biomedicine & Pharmacotherapy · 2023 · DOI verified

Programme 02

Sports medicine & joint reconstruction

Studies and evidence syntheses concerning ACL reconstruction, rotator-cuff surgery, and postoperative structural outcomes. Procedure choice remains patient- and context-specific.

  1. Gradual stabilization and narrowing of bone tunnels following primary anterior cruciate ligament reconstruction

    Longitudinal report of bone-tunnel change after primary ACL reconstruction; it does not by itself determine graft or follow-up choice.

    Knee Surgery, Sports Traumatology, Arthroscopy · 2024 · DOI verified
  2. Outcomes from different aspects indicate the all-inside technique may serve as an ideal option for anterior cruciate ligament reconstruction

    Comparative evidence synthesis whose conclusions should be read with its methods, included studies, and limitations.

    Knee Surgery, Sports Traumatology, Arthroscopy · 2024 · DOI verified
  3. Surgical management for massive rotator cuff tears: a network meta-analysis of randomized controlled trials

    Network meta-analysis of randomized trials; treatment rankings are not an individual surgical recommendation.

    Burns & Trauma · 2024 · DOI verified

Programme 03

Foot, ankle & paediatric orthopaedics

Evidence syntheses and clinical reviews spanning PRP, Achilles tendinopathy, and paediatric cavovarus foot.

  1. Advances in the clinical application of platelet-rich plasma in the foot and ankle: a review

    Clinical review mapping proposed applications, evidence gaps, and translational limitations; it is not proof that PRP benefits every condition.

    Journal of Clinical Medicine · 2023 · DOI verified
  2. The efficacy of platelet-rich plasma injection therapy in the treatment of patients with Achilles tendinopathy: a systematic review and meta-analysis

    Systematic review and meta-analysis assessing efficacy; interpretation remains conditional on the included trials and their heterogeneity.

    Journal of Clinical Medicine · 2023 · DOI verified
  3. Current advancements in diagnosing and managing cavovarus foot in paediatric patients

    Clinical review of diagnostic and management considerations in paediatric cavovarus foot.

    EFORT Open Reviews · 2024 · DOI verified

Programme 04

Musculoskeletal ageing, osteoporosis & rehabilitation

Evidence syntheses concerning osteoporosis treatment, physical activity, mortality, and symptom-management modalities. Association, efficacy, and clinical recommendation are kept distinct.

  1. Teriparatide in postmenopausal osteoporosis: uncovering novel insights into efficacy and safety compared to other treatments – a systematic review and meta-analysis

    Systematic review and meta-analysis comparing efficacy and safety outcomes; treatment decisions require individual fracture-risk assessment.

    EFORT Open Reviews · 2024 · DOI verified
  2. Associations between exercise training, physical activity, sedentary behaviour and mortality: an umbrella review of meta-analyses

    Umbrella review of meta-analyses reporting associations; observational evidence is not described as proof of a single causal effect.

    Journal of Cachexia, Sarcopenia and Muscle · 2025 · DOI verified
  3. Cryotherapy and thermotherapy in the management of osteoarthritis and rheumatoid arthritis: a comprehensive review

    Comprehensive review of symptom-management evidence and research gaps; DOI metadata records the journal year as 2025.

    Fundamental Research · 2025 · DOI verified